OptiQuant®-S HCV Quantification Panel
Based on the revolutionary SynTura™ Technology, the OptiQuant-S HCV Quantification panel provides laboratories with the largest reportable range commercially available and is developed for use on various automated HCV NAT systems. Use the OptiQuant-S HCV panel to establish or verify performance specifications for accuracy, precision, reportable range, and analytical sensitivity and specificity. This product is For Research Use Only. Not for use in diagnostic procedures.
Procedure
The OptiQuant-S HCV Quantification Panel members have been carefully formulated to mimic naturally occurring human specimens containing HCV. Additionally, the intact virus format of the panel members allows for verification of an effective viral RNA extraction procedure. Because the panel members contain intact, viral particles, the test methodology should include an extraction step that releases the viral RNA and makes it available for transcription, amplification, and/or hybridization, as appropriate to the test.
Interpretation of Results
The OptiQuant-S HCV Quantification Panel provides traceable results in accordance with the ISO 17511 standard. Because each panel member is calibrated against the WHO International Standard for HCV RNA, the assigned values and measurement uncertainties are reported as International Units per milliliter (IU/mL). Commercial or homebrew test procedures may report results in units that differ from International Units as defined by WHO. Assigned values are manufacturing targets and may not represent actual results obtained by the laboratory. The performance characteristics of the OptIQuant-S HCV Quantification Panel should be established by each laboratory.
Product Description
The OptiQuant-S HCV Quantification Panel members were produced by making quantitative dilutions of SynTura HCV, a modified Flaviviridae containing the entire HCV 5’ UTR, developed using SynTura Technology, into normal human plasma (NHP) with EDTA. The NHP was previously tested and found to be non-reactive for HBV DNA, HCV RNA, HIV-1 RNA, antibodies to HIV-1 and HIV-2, HBsAg, antibodies to HCV, and antibodies to HTLV I-II.
Each panel member contains 0.05% sodium azide and 0.05% gentamicin sulfate as preservatives.
Panel Configuration
| Description | Catalog Number |
|---|---|
| OptiQuant®-S HCV Quantification Panel | 95-0350 |
| Configurations | |
| OptiQuant-S HCV 1E2 | 1.2mL |
| OptiQuant-S HCV 5E2 | 1.2mL |
| OptiQuant-S HCV 5E3 | 1.2mL |
| OptiQuant-S HCV 5E4 | 1.2mL |
| OptiQuant-S HCV 5E5 | 1.2mL |
| OptiQuant-S HCV 5E6 | 1.2mL |
| OptiQuant-S HCV 2.5E7 | 1.2mL |
The OptiQuant-S HCV Quantification Panel must be stored at -20°C or lower to ensure highest quality. Discard any unused material after use.